|
KMID : 1041219990410010009
|
|
Journal of Sericultural and Entomological Science
1999 Volume.41 No. 1 p.9 ~ p.13
|
|
|
Pharmacodynamic Study of Silkworm Powder in Mice Administered to Maltose, Sucrose and Lactose
|
|
Ryu Kang-Sun
Lee Heui-Sam
Kim Sun-Yeou
|
|
|
Abstract
|
|
|
|
The experiment was carried out to investigate the absorption profile of blood glucose in mice administered to silkworm powder MeOH extract. The mice was injected to oral load of maltose, sucrose and lactose(2 g/kg) and silkworm powder MeOH extract at the same time. After injecting the sample, blood glucose concentration was measured at 0, 30, 60, 120, 180 and 240 minutes. Blood glucose lowering effect of silkworm powder for loading maltose was 69% in postprandial 30 minutes. After the postprandial 60 minutes, the glucose was absorbed slowly. Total amount of blood glucose absorption in mice administered to maltose were 560.7 mg/dl during 240 minutes. That of silkworm powder MeOH extract marked 534.7 mg/dl. Total amount of blood glucose from oral loading sucrose reached to 508.9 mg/dl. That of loading silkworm powder MeOH extract were 468.8. But, silkworm powder was not inhibited lactose absorption. As a above results, silkworm powder inhibits the transient rising of blood glucose after postprandial 30 minuts through inhibition of -glucosidases. In case of starvation silkworm powder don’t promote the hypoglycemia. In addition, silkworm powder induces the delay absorption of glucose without loss of it.
|
|
|
KEYWORD
|
|
|
Silkworm powder, Pharmacodynamic, Absorption
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|
|
|